PIK3C2A anticorps (C-Term)

N° du produit ABIN5534605

Détail du produit anti-PIK3C2A anticorps

Antigène: PIK3C2A (Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))

Épitope: AA 1431-1458, C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3C2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PIK3C2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1431-1458 amino acids from the C-terminal region of human PIK3C2A.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PIK3C2A

Antigène: PIK3C2A (Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))

Autre désignation: PIK3C2A (PIK3C2A Produits)

Synonymes: anticorps CPK, anticorps PI3-K-C2(ALPHA), anticorps PI3-K-C2A, anticorps cpk, anticorps pi3-k-c2a, anticorps Cpk-m, anticorps PI3KC2, anticorps sb:cb156, anticorps si:dkey-24l11.7, anticorps wu:fc02a04, anticorps phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha, anticorps phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha, anticorps phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha S homeolog, anticorps phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, anticorps PIK3C2A, anticorps Pik3c2a, anticorps pik3c2a, anticorps pik3c2a.S, anticorps LOC100548137

Sujet: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.

Poids moléculaire: 191 kDa

ID gène: 5286

UniProt: O00443

Pathways: EGFR Signaling Pathway, Inositol Metabolic Process, Platelet-derived growth Factor Receptor Signaling