This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Immunogène
This CYP8B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 471-501 amino acids from the C-terminal region of human CYP8B1.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
CYP8B1
(Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1))
anticorps MGC64456, anticorps CYP8B, anticorps CP8B, anticorps CYP12, anticorps cytochrome P450 family 8 subfamily B member 1, anticorps cytochrome P450 family 8 subfamily B member 1 S homeolog, anticorps cytochrome P450, family 8, subfamily B, polypeptide 1, anticorps cytochrome P450, family 8, subfamily b, polypeptide 1, anticorps Cyp8b1, anticorps cyp8b1.S, anticorps CYP8B1
Sujet
CYP8B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless.