FBXW8 anticorps (AA 270-299)

N° du produit ABIN5536476

Détail du produit anti-FBXW8 anticorps

Antigène: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Épitope: AA 270-299

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXW8 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This FBXW8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-299 amino acids from the Central region of human FBXW8.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur FBXW8

Antigène: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Autre désignation: FBXW8 (FBXW8 Produits)

Synonymes: anticorps FBW6, anticorps FBW8, anticorps FBX29, anticorps FBXO29, anticorps FBXW6, anticorps 4930438M06Rik, anticorps Fbx29, anticorps F-box and WD repeat domain containing 8, anticorps ring finger protein, transmembrane 2, anticorps F-box and WD-40 domain protein 8, anticorps FBXW8, anticorps Fbxw8, anticorps RNFT2

Sujet: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Poids moléculaire: 67 kDa

ID gène: 26259

UniProt: Q8N3Y1