SEC63 anticorps (N-Term)

N° du produit ABIN5537506

Détail du produit anti-SEC63 anticorps

Antigène: SEC63 (SEC63 Homolog (SEC63))

Épitope: AA 139-168, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEC63 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SEC63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-168 amino acids from the N-terminal region of human SEC63.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SEC63

Antigène: SEC63 (SEC63 Homolog (SEC63))

Autre désignation: SEC63 (SEC63 Produits)

Synonymes: anticorps DNAJC23, anticorps ERdj2, anticorps PRO2507, anticorps SEC63L, anticorps 5730478J10Rik, anticorps AI649014, anticorps AW319215, anticorps SEC63-like, anticorps zgc:92718, anticorps SEC63 homolog, protein translocation regulator, anticorps SEC63-like (S. cerevisiae), anticorps SEC63 homolog, protein translocation regulator L homeolog, anticorps SEC63, anticorps Sec63, anticorps sec63, anticorps sec63.L

Sujet: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

Poids moléculaire: 88 kDa

ID gène: 11231

UniProt: Q9UGP8

Pathways: ER-Nucleus Signaling