SRSF2 anticorps (AA 76-105)

N° du produit ABIN5537524

Détail du produit anti-SRSF2 anticorps

Antigène: SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

Épitope: AA 76-105

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRSF2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This SFRS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the Central region of human SFRS2.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SRSF2

Antigène: SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

Autre désignation: SFRS2 (SRSF2 Produits)

Synonymes: anticorps PR264, anticorps SC-35, anticorps SC35, anticorps SFRS2, anticorps SFRS2A, anticorps SRp30b, anticorps D11Wsu175e, anticorps MRF-1, anticorps Pr264, anticorps Sfrs10, anticorps Sfrs2, anticorps pr264, anticorps sc-35, anticorps sc35, anticorps sfrs2, anticorps sfrs2a, anticorps srp30b, anticorps serine and arginine rich splicing factor 2, anticorps serine/arginine-rich splicing factor 2, anticorps serine/arginine-rich splicing factor 2 L homeolog, anticorps SRSF2, anticorps Srsf2, anticorps srsf2.L

Sujet: SFRS2 is necessary for the splicing of pre-mRNA. The protein is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. And it interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. It binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3' and can bind to beta-globin mRNA and commit it to the splicing pathway.

Poids moléculaire: 25 kDa

ID gène: 6427

UniProt: Q01130