c-MET anticorps

N° du produit ABIN5542211

Cet anticorps Rat Monoclonal détecte spécifiquement c-MET dans FACS et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour c-MET anticorps (ABIN5542211)

Antigène: c-MET (MET) (Met Proto-Oncogene (MET))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp c-MET est non-conjugé

Application: Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone: BCI-3E7

Détail du produit anti-c-MET anticorps

Specificité: Recognizes c-Met. Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells.

Purification: Affinity Chromatography on Protein G

Immunogène: cDNA encoding Human c-Met

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry: 1.2 μg/10 6 cells. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.2

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur c-MET

Antigène: c-MET (MET) (Met Proto-Oncogene (MET))

Autre désignation: hgf receptor

Sujet: C-MET is a receptor tyrosine kinase that is activated upon Hepatocyte Growth Factor (HGF) binding. c-MET is produced as a single-chain precursor and plays en essential role in embryonic development and wound healing. It belongs to the class of Singlepass type I membrane proteins and it is normally expressed by cells of epithelial origin while the expression of HGF is restricted to cells of mesenchymal origin in an almost perfect paracrine paradigm. Overexpression of c-MET can be found in several kinds of tumor progression.

UniProt: P08581

Pathways: Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor