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c-MET anticorps (C-Term)

Name: c-MET anticorps (C-Term)
Brand: antibodies-online
SKU: ABIN2854819
Price: 660.63 EUR
Availability: InStock

MET Reactivité: Humain WB, IF, ICC, IP Hôte: Lapin Polyclonal unconjugated

WB Image Sample(30 ug whole cell lysate) A:HeLa S3, 5% SDS PAGE antibody diluted at 1:1000 (c-MET anticorps (C-Term))

ICC/IF Image c-Met antibody [c3], c-term detects c-Met protein at cytoplasm by immunofluorescent analysis. (c-MET anticorps (C-Term))

IHC-P Image Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using c-Met, antibody at 1:100 dilution. (c-MET anticorps (C-Term))

IHC

IP Image Immunoprecipitation of c-Met protein from HeLa whole cell extracts using 5 μg of c-Met antibody [C3], C-term, Western blot analysis was performed using c-Met antibody [C3], C-term, EasyBlot anti-Rabbit IgG was used as a secondary reagent. (c-MET anticorps (C-Term))

MUC20 knockdown inhibits HGF/MET signalling in PDAC cells. (c-MET anticorps (C-Term))

5 images

N° du produit ABIN2854819

Fiche de données

Antigène Voir toutes c-MET (MET) Anticorps

c-MET (MET) (Met Proto-Oncogene (MET))
Épitope
49

35

28

21

16

11

11

8

7

7

7

6

5

5

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reactivité
250

144

98

8

6

4

4

4

2

2

2

1

1

1

1
Humain
Hôte
221

39

3

2
Lapin
Anticorps secondaires appropriés
Clonalité
209

56
Polyclonal
Conjugué
131

20

13

12

9

9

9

9

9

9

8

7

3

3

3

3

3

1

1

1

1

1
Cet anticorp c-MET est non-conjugé
Application
181

105

51

43

30

27

26

24

14

8

7

7

4

4

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Réactivité croisée

Chimpanzé

Réactivité croisée (Details)

Chimpanzee (100 %)

Attributs du produit

Rabbit Polyclonal antibody to MET (met proto-oncogene (hepatocyte growth factor receptor))
c-Met antibody [C3], C-term

Purification

Purified by antigen-affinity chromatography.

Immunogène

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human c-Met. The exact sequence is proprietary.

Isotype

IgG

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anti-Met Proto-Oncogene (MET) (Tyr1003) antibody
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MET Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-Met Proto-Oncogene (MET) (pTyr1003) antibody
MET Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated

Indications d'application

Suggested dilution Reference ICC/IF 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*

Commentaires

Positive Control: HeLaS3

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur

Thimerosal (Merthiolate)

Précaution d'utilisation

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Antigène

c-MET (MET) (Met Proto-Oncogene (MET))

Autre désignation

C-Met (MET Produits)

Synonymes

anticorps AUTS9, anticorps HGFR, anticorps RCCP2, anticorps c-Met, anticorps AI838057, anticorps HGF, anticorps Par4, anticorps Hgfr, anticorps c-met, anticorps MET, anticorps C-MET, anticorps met, anticorps met-A, anticorps MET proto-oncogene, receptor tyrosine kinase, anticorps met proto-oncogene, anticorps MET proto-oncogene, receptor tyrosine kinase L homeolog, anticorps MET, anticorps Met, anticorps met.L

Sujet

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Membrane, Single-pass type I membrane protein

Poids moléculaire

156 kDa

ID gène

4233

Pathways

Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor