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c-MET anticorps (AA 743-932)

MET Reactivité: Humain WB, ELISA, IHC, FACS, ICC Hôte: Souris Monoclonal 5E9B7 unconjugated
N° du produit ABIN5542708
  • Antigène Voir toutes c-MET (MET) Anticorps
    c-MET (MET) (Met Proto-Oncogene (MET))
    Épitope
    • 49
    • 35
    • 28
    • 21
    • 16
    • 12
    • 11
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 743-932
    Reactivité
    • 250
    • 144
    • 98
    • 8
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 222
    • 38
    • 3
    • 2
    Souris
    Clonalité
    • 210
    • 55
    Monoclonal
    Conjugué
    • 131
    • 20
    • 13
    • 12
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp c-MET est non-conjugé
    Application
    • 181
    • 104
    • 50
    • 42
    • 31
    • 27
    • 26
    • 24
    • 14
    • 8
    • 8
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Immunogène
    Purified recombinant fragment of human MET (AA 743-932) expressed in E. Coli.
    Clone
    5E9B7
    Isotype
    IgG2a
    Top Product
    Discover our top product MET Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: 1:100 - 1:500, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.05 % sodium azide
    Stock
    4 °C,-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Antigène
    c-MET (MET) (Met Proto-Oncogene (MET))
    Autre désignation
    MET (MET Produits)
    Synonymes
    anticorps AUTS9, anticorps HGFR, anticorps RCCP2, anticorps c-Met, anticorps AI838057, anticorps HGF, anticorps Par4, anticorps Hgfr, anticorps c-met, anticorps MET, anticorps C-MET, anticorps met, anticorps met-A, anticorps MET proto-oncogene, receptor tyrosine kinase, anticorps met proto-oncogene, anticorps MET proto-oncogene, receptor tyrosine kinase L homeolog, anticorps MET, anticorps Met, anticorps met.L
    Sujet
    This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.,
    Poids moléculaire
    18.6kDa
    HGNC
    1153
    Pathways
    Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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