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CLCN2 anticorps (Internal Region)
CLCN2
Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien
WB, EIA
Hôte: Chèvre
Polyclonal
unconjugated
Détail du produit anti-CLCN2 anticorps
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Antigène
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CLCN2
(Chloride Channel 2 (CLCN2))
Épitope
Tous les épitopes à travers CLCN2 Anticorps.
Internal Region
Reactivité
Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien
Hôte
Toutes les hôtes sur CLCN2 Anticorps
Chèvre
Clonalité
Toutes les clonalités sur CLCN2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CLCN2 Anticorps
Cet anticorp CLCN2 est non-conjugé
Application
Tous les applications à travers CLCN2 Anticorps.
Western Blotting (WB), Enzyme Immunoassay (EIA)
Séquence
QQLDEPVNFS DCK
Specificité
This antibody is expected to recognize all reported isoforms (NP_004357.3, NP_001164558.1, NP_001164559.1, NP_001164560.1).
Réactivité croisée (Details)
Species reactivity (expected):Mouse, Rat, Canine (Dog), Cow, Rabbit . Species reactivity (tested):Human.
Purification
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
Immunogène
Peptide with sequence from the internal region of the protein sequence according to NP_004357.3. Genename: CLCN2
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur CLCN2
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Antigène
CLCN2
(Chloride Channel 2 (CLCN2))
Autre désignation
CLCN2 (CLCN2 Produits )
Synonymes
anticorps CLCN2, anticorps CLC2, anticorps LOC100150892, anticorps AL118368, anticorps ClC-2, anticorps Clc2, anticorps nmf240, anticorps CLC-2, anticorps CIC-2, anticorps ECA2, anticorps ECA3, anticorps EGI11, anticorps EGI3, anticorps EGMA, anticorps EJM6, anticorps EJM8, anticorps clC-2, anticorps chloride voltage-gated channel 2, anticorps chloride channel, voltage-sensitive 2a, anticorps chloride channel protein 2, anticorps chloride channel, voltage-sensitive 2, anticorps CLCN2, anticorps clcn2a, anticorps EHI_142170, anticorps EHI_186860, anticorps Clcn2
Sujet
CLCN2 is a voltage-gated chloride channel, a class of proteins that have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This protein is ubiquitously expressed, with moderate expression in aortic and coronary vascular smooth muscle cells and low levels expressed in aortic endothelial cells. Defects in CLCN2 may be the cause of epilepsy with grand mal seizures on awakening, childhood absence epilepsy type 3, and juvenile absence epilepsy. Single nucleotide polymorphisms (SNPs) of CLCN2 may also at as potential modifiers of cystic fibrosis disease severity.Synonyms: CIC-2, CIC2, CLC3, Chloride channel protein 2
ID gène
1181
NCBI Accession
NP_001164558
UniProt
P51788
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