Cet anticorps anti-c-MET Polyclonal Lapin (ABIN5611438) détecte spécifiquement c-MET dans IHC (p).
L’anticorps est réactif avec des échantillons de Humain.
MET
Reactivité: Humain, Souris, Rat
WB, ELISA, IF, ICC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
0,2 mg/mL
Buffer
10 mM PBS/1 % BSA buffer pH 7.4 with 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Antigène
c-MET (MET)
(Met Proto-Oncogene (MET))
Autre désignation
HGF Receptor
Sujet
Met, an HGF Receptor/Met type protein kinase, is a cell-surface proto-oncogene that mediates the biological activities of hepatocyte growth factor. The protein is a disulfide-linked heterodimer comprised of two subunits: a 50 kD extracellular alpha subunit and a membrane-spanning 145 kD beta subunit that binds ligand. Met is an important regulator of cell proliferation and differentiation, organ regeneration, embryogenesis, and tumorogenesis. Constitutive activation mutations of the met gene lead to many cancers, particularly renal papillary carcinoma.Synonyms: HGF/SF receptor, Hepatocyte growth factor receptor, MET, Met proto-oncogene tyrosine kinase, Scatter factor receptor, c-Met