BCL2A1 anticorps

N° du produit ABIN1678494

Détail du produit anti-BCL2A1 anticorps

Antigène: BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL2A1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide of human BCL2A1

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Avoid freeze / thaw cycles.

Détails sur BCL2A1

Antigène: BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

Autre désignation: BCL2A1 (BCL2A1 Produits)

Synonymes: anticorps ACC-1, anticorps ACC-2, anticorps BCL2L5, anticorps BFL1, anticorps GRS, anticorps HBPA1, anticorps Bcl2a1d, anticorps BCL2A1, anticorps BCL2 related protein A1, anticorps BCL2-related protein A1, anticorps BCL2A1, anticorps Bcl2a1

Sujet: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,BCL2A1,ACC-1,ACC-2,ACC1,ACC2,BCL2L5,BFL1,GRS,HBPA1,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,B Cell Receptor Signaling Pathway,BCL2A1

Poids moléculaire: 18 kDa/20 kDa

ID gène: 597

UniProt: Q16548