Recombinant p53 anticorps (AA 371-380)

N° du produit ABIN5668086

Cet anticorps Lapin Chimeric détecte spécifiquement p53 dans WB, ELISA, IF, IHC (p), IP, IHC (fro) et in vivo. Il présente une réactivité envers Humain, Souris, Rat, Singe et Lapin.

Aperçu rapide pour Recombinant p53 anticorps (AA 371-380) (ABIN5668086)

Antigène: p53 (TP53) (Tumor Protein P53 (TP53))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat, Singe, Lapin

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp p53 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), In vivo Studies (in vivo)

Clone: PAb421

Détail du produit anti-p53 anticorps

Épitope: AA 371-380

Fonction: Anti-p53 [PAb421], Rabbit IgG, kappa

Specificité: Recognises the mammalian mutant and wild-type p53 protein and reacts with an epitope between amino acid residues 370 and 378 (near the C-terminus of the protein), corresponding to the sequence "KKGQSTSRHK".

Réactivité croisée: Singe, Souris, Lapin, Rat

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogène: Synthetic peptide corresponding to aa 371-380 of human p53.

Isotype: IgG kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur p53

Antigène: p53 (TP53) (Tumor Protein P53 (TP53))

Autre désignation: p53

Sujet: Tumor suppressor p53, Cellular tumor antigen p53

UniProt: P04637

Pathways: Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg