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Androgen Receptor anticorps

AR Reactivité: Humain IHC (p), IHC (fro) Hôte: Souris Monoclonal F39-4-1 unconjugated
N° du produit ABIN5680093
  • Antigène Voir toutes Androgen Receptor (AR) Anticorps
    Androgen Receptor (AR)
    Reactivité
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    Humain
    Hôte
    • 254
    • 50
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    Souris
    Clonalité
    • 246
    • 59
    Monoclonal
    Conjugué
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    Cet anticorp Androgen Receptor est non-conjugé
    Application
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    Human androgen receptor, 110 kDa protein in lysate of LNCP cell line.
    Réactivité croisée (Details)
    Human
    Attributs du produit
    The antibody to androgen receptors binds to these proteins in nuclei of typical normal tissues. Over-expression may be observed in tumours like prostate carcinoma and osteosarcoma. For information transmission to the target cells male steroid hormones like Testosterone and DHT require a specific receptor. This specific receptor, called androgen receptor, is found in numerous human tissues like skin, mucous membranes, seminal vesicles, prostate gland and testis. Androgen receptors will also be found in human tumours like prostate carcinoma, osteosarcoma and others. In prostate carcinoma the clinical relevance has been proven by castration and androgen deprivation by Gn-RH-agonist and -antagonist treatment. In many cases androgen deprivation slows down tumour growth in androgen-dependent prostate carcinoma. Human androgen receptor, 110 kDa protein in lysate of LNCP cell line..
    Purification
    Antibody solution
    Immunogène
    Synthetic peptide
    Clone
    F39-4-1
    Isotype
    IgG1
    Top Product
    Discover our top product AR Anticorps primaire
  • Indications d'application
    Heat pre-treatment of formalin-fixed tissue with Unmasking Fluid C or G ,Testis,IHC(C, P),60 min at RT,(liquid conc.) 1:5 - 1:20
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    stabilizing phosphate buffer  pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 μL working solution / test)
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Antigène
    Androgen Receptor (AR)
    Autre désignation
    Androgen Receptor (AR Produits)
    Synonymes
    anticorps AIS, anticorps DHTR, anticorps HUMARA, anticorps HYSP1, anticorps KD, anticorps NR3C4, anticorps SBMA, anticorps SMAX1, anticorps TFM, anticorps AW320017, anticorps Tfm, anticorps Andr, anticorps AR, anticorps androgen receptor, anticorps AR, anticorps Ar, anticorps ar
    Pathways
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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