AIMP1 anticorps

N° du produit ABIN5687576

Détail du produit anti-AIMP1 anticorps

Antigène: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp AIMP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Anti-hEMAP-II specific antibody was purified by affinity chromatography employing immobilized hEMAP-II matrix.

Immunogène: Produced from sera of goats pre-immunized with highly pure (>98%) recombinant hEMAP-II (human EMAP-II).

Information d'application

Indications d'application: ELISA:

To detect hEMAP-II by direct ELISA (using 100 μ,L/well antibody solution) a concentration of at least 0.5 μ,g/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant hEMAP-II.

Sandwich: To detect hEMAP-II by sandwich ELISA (using 100 μ,L/well antibody solution) a concentration of 0.5 - 2.0 μ,g/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our Biotinylated Anti-Human EMAP-II (XP-5122Bt) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hEMAP-II.

Western Blot:

To detect hEMAP-II by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μ,g/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hEMAP-II is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Stock: -20 °C

Stockage commentaire: EMAP-II antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. Avoid repeated freeze-thaw cycles.

Détails sur AIMP1

Antigène: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Autre désignation: EMAP-II (AIMP1 Produits)

Synonymes: anticorps EMAP2, anticorps EMAPII, anticorps HLD3, anticorps SCYE1, anticorps p43, anticorps wu:fa95a05, anticorps zgc:154081, anticorps AIMP1, anticorps 9830137A06Rik, anticorps AIMP1/p43, anticorps Emap2, anticorps Scye1, anticorps scye1, anticorps aminoacyl tRNA synthetase complex interacting multifunctional protein 1, anticorps aminoacyl tRNA synthetase complex-interacting multifunctional protein 1, anticorps aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 S homeolog, anticorps AIMP1, anticorps aimp1, anticorps Aimp1, anticorps aimp1.S

Sujet: EMAP II is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor associated vasculature sensitive to tumor necrosis factor. Its precursor is identical to the p43 subunit, which is associated with the multi tRNA synthetase complex. Therefore, proEMAP II may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells. EMAP II inhibits angiogenesis of vascular beds and suppresses the growth of primary and secondary tumors without affecting normal tissues.

ID gène: 9255

UniProt: Q12904