TNFRSF10A anticorps (Atto 647N)

N° du produit ABIN5688381

Détail du produit anti-TNFRSF10A anticorps (Atto 647N)

Antigène: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFRSF10A est conjugé à/à la Atto 647N

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Specificité: Recognizes human TRAIL-R1. Does not cross-react with human TRAIL-R2, -R3 or -R4.

Pureté: > 95% (SDS-PAGE)

Immunogène: Recombinant human TRAIL-R1 (DR4).

Clone: HS101

Isotype: IgG1

Information d'application

Indications d'application: Definition for 1 test: 1 μL of labeled antibody in 200 μL of Flow Cytometry buffer (see online protocol).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.

Détails sur TNFRSF10A

Antigène: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Autre désignation: TRAIL-R1 (TNFRSF10A Produits)

Synonymes: anticorps APO2, anticorps CD261, anticorps DR4, anticorps TRAILR-1, anticorps TRAILR1, anticorps TNFRSF10A, anticorps TNF receptor superfamily member 10a, anticorps tumor necrosis factor receptor superfamily member 26, anticorps tumor necrosis factor receptor superfamily, member 10a, anticorps TNFRSF10A, anticorps LOC510798

Sujet: TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.

ID gène: 8797

UniProt: O00220

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity