LAMTOR2 anticorps (AA 40-90)

N° du produit ABIN5690038

Détail du produit anti-LAMTOR2 anticorps

Antigène: LAMTOR2 (Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 2 (LAMTOR2))

Épitope: AA 40-90

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LAMTOR2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: LAMTOR2 antibody is human, mouse and rat reactive. At least two isoforms of LAMTOR2 are known to exist, this antibody will detect both isoforms. LAMTOR2 antibody is predicted to not cross-react with other LAMTOR family proteins.

Purification: LAMTOR2 antibody is affinity chromatography purified via peptide column.

Immunogène: LAMTOR2 antibody was raised against an 18 amino acid peptide near the center of human LAMTOR2.

The immunogen is located within amino acids 40 - 90 of LAMTOR2.

Isotype: IgG

Information d'application

Indications d'application: LAMTOR2 antibody can be used for detection of LAMTOR2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: LAMTOR2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: LAMTOR2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur LAMTOR2

Antigène: LAMTOR2 (Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 2 (LAMTOR2))

Autre désignation: LAMTOR2 (LAMTOR2 Produits)

Synonymes: anticorps ENDAP, anticorps HSPC003, anticorps MAPBPIP, anticorps MAPKSP1AP, anticorps ROBLD3, anticorps Ragulator2, anticorps p14, anticorps 2010111E04Rik, anticorps AL022628, anticorps Mapbpip, anticorps P14, anticorps Rab25, anticorps Robld3, anticorps RGD1562501, anticorps cg5189, anticorps endap, anticorps hspc003, anticorps mapbpip, anticorps mapbpip-B, anticorps mapksp1ap, anticorps ragulator2, anticorps robld3, anticorps robld3-b, anticorps zgc:100811, anticorps lamtor2, anticorps lamtor2-a, anticorps lamtor2-b, anticorps mapbpip-A, anticorps robld3-a, anticorps late endosomal/lysosomal adaptor, MAPK and MTOR activator 2, anticorps late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 S homeolog, anticorps late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 L homeolog, anticorps LAMTOR2, anticorps Lamtor2, anticorps lamtor2.S, anticorps lamtor2, anticorps lamtor2.L

Sujet: The late endosomal/lysosomal adaptor MAPK and MTOR activator 2 (LAMTOR2) protein belongs to the LAMTOR family of proteins, and together with LAMTOR3 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling (1,2). This complex is involved in the regulation of late endosomal traffic and cellular proliferation (3) and plays a role in cellular host defense against Salmonella infection (4).

Poids moléculaire: Predicted: 14 kDa

Observed: 16 kDa

ID gène: 28956

NCBI Accession: NP_054736

UniProt: Q9Y2Q5

Pathways: Signalisation PI3K-Akt