TRIM33 anticorps (AA 580-630)

N° du produit ABIN5690302

Détail du produit anti-TRIM33 anticorps

Antigène: TRIM33 (Tripartite Motif Containing 33 (TRIM33))

Épitope: AA 580-630

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM33 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: TRIM33 antibody is human, mouse and rat reactive. At least two isoforms of TRIM33 are known to exist.

Purification: TRIM33 Antibody is affinity chromatography purified via peptide column.

Immunogène: TRIM33 antibody was raised against an 18 amino acid peptide near the center of human TRIM33.

The immunogen is located within amino acids 580 - 630 of TRIM33.

Isotype: IgG

Information d'application

Indications d'application: TRIM33 antibody can be used for detection of TRIM33 by Western blot at 1 - 2 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TRIM33 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: TRIM33 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur TRIM33

Antigène: TRIM33 (Tripartite Motif Containing 33 (TRIM33))

Autre désignation: TRIM33 (TRIM33 Produits)

Synonymes: anticorps TRIM33, anticorps ptc7, anticorps rfg7, anticorps tf1g, anticorps tif1g, anticorps tifgamma, anticorps MGC146665, anticorps tif1gamma, anticorps ECTO, anticorps PTC7, anticorps RFG7, anticorps TF1G, anticorps TIF1G, anticorps TIF1GAMMA, anticorps TIFGAMMA, anticorps ecto, anticorps 8030451N04Rik, anticorps AI413936, anticorps Ecto, anticorps Tif1g, anticorps ectodermin, anticorps mKIAA1113, anticorps cb1085, anticorps id:ibd2175, anticorps mon, anticorps wu:fc17f10, anticorps zgc:136680, anticorps tripartite motif containing 33, anticorps tripartite motif containing 33 L homeolog, anticorps tripartite motif-containing 33, anticorps TRIM33, anticorps trim33, anticorps trim33.L, anticorps Trim33

Sujet: TRIM33 Antibody: TRIM24 (TIF1alpha), TRIM28 (TIF1beta), and TRIM33 (TIF1gamma) are three related cofactors belonging to the tripartite motif superfamily that interact with distinct transcription factors (1-2). The structure of TRIM33 is similar to TRIM24 and TRIM28, exhibiting multiple domains (RING finger, coiled coil, B boxes, PHD/TTC, and bromodomain) (3). TRIM33 functions in cell differentiation and development, playing a role in differentiation of hematopoietic cells (3). It interacts with the Smad2/3 transcription factor in hematopoietic, mesenchymal, and epithelial cell types to mediate different transcriptional effects in response to TGF-beta (4). It acts as an E3 ubiquitin-protein ligase and promotes SMAD4 ubiquitination (5).

Poids moléculaire: Predicted: 70, 124 kDa

Observed: 70 kDa

ID gène: 51592

NCBI Accession: NP_056990

UniProt: Q9UPN9