IDO1 anticorps
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- Antigène Voir toutes IDO1 Anticorps
- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IDO1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Specificité
- Recognizes human IDO. Detects a band of ~45 kDa by Western blot.
- Immunogène
- Recombinant human IDO.
- Top Product
- Discover our top product IDO1 Anticorps primaire
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- Indications d'application
- ELISA: (direct and indirect: 1:2,000-1:10,000). Flow Cytometry: (1:200-1:500). Immunocytochemistry: (1:500) . Western Blot: (1:2,000-1:5,000 using ECL, suggested blocking and dilution buffer is PBST containing 0.05 % Tween 20 and 5 % skim milk, suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
- Agent conservateur
- Without preservative
- Stock
- -20 °C
- Stockage commentaire
- Stable for at least 6 months after receipt when stored at -20°C.
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- Antigène
- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
- Autre désignation
- IDO (IDO1 Produits)
- Synonymes
- anticorps INDO, anticorps ido, anticorps indo, anticorps IDO, anticorps cd107b, anticorps IDO1, anticorps IDO-1, anticorps Ido, anticorps Indo, anticorps indoleamine 2,3-dioxygenase 1, anticorps indoleamine 2,3-dioxygenase 1 L homeolog, anticorps indoleamine 2,3-dioxygenase 1-like, anticorps IDO1, anticorps ido1.L, anticorps ido1, anticorps Ido1, anticorps LOC100050681
- Sujet
- IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
- ID gène
- 3620
- NCBI Accession
- NP_002155
- UniProt
- P14902
- Pathways
- Activated T Cell Proliferation
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