IDH2 anticorps (Internal Region)
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- Antigène Voir toutes IDH2 Anticorps
- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat, Porc, Boeuf (Vache), Chien
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IDH2 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Séquence
- CIHGLSNVKL NE
- Specificité
- Recognizes Isocitrate Dehydrogenase / IDH2
- Réactivité croisée (Details)
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Species reactivity (expected):Canine (Dog), Bovine, Pig.
Species reactivity (tested):Human, Mouse, Rat. - Purification
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
- Immunogène
- Peptide with sequence from the internal region of the protein sequence according to NP_002159.2. Genename: IDH2
- Top Product
- Discover our top product IDH2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
- Autre désignation
- Isocitrate Dehydrogenase / IDH2 (IDH2 Produits)
- Synonymes
- anticorps F6P23.14, anticorps F6P23_14, anticorps IDH-II, anticorps NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 2, anticorps isocitrate dehydrogenase II, anticorps isocitrate dehydrogenase subunit 2, anticorps D2HGA2, anticorps ICD-M, anticorps IDH, anticorps IDHM, anticorps IDP, anticorps IDPM, anticorps mNADP-IDH, anticorps E430004F23, anticorps IDPm, anticorps Idh-2, anticorps wu:fb33c06, anticorps wu:fk31e05, anticorps wu:fq43b01, anticorps zgc:55485, anticorps idh2, anticorps IDH2, anticorps isocitrate dehydrogenase subunit 2, anticorps isocitrate dehydrogenase (NADP(+)) 2, mitochondrial, anticorps isocitrate dehydrogenase 2 (NADP+), mitochondrial, anticorps isocitrate dehydrogenase 2 (NADP+), mitochondrial S homeolog, anticorps isocitrate dehydrogenase [NADP], mitochondrial, anticorps IDH2, anticorps Idh2, anticorps idh2.S, anticorps idh2, anticorps LOC100441867
- Sujet
- Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.Synonyms: ICD-M, ICDH, IDP, NADP(+)-specific ICDH, mitochondrial Isocitrate dehydrogenase [NADP], mitochondrial Oxalosuccinate decarboxylase
- Poids moléculaire
- 50.9kDa (NP_002159.2).
- ID gène
- 3418
- NCBI Accession
- NP_002159
- UniProt
- P48735
- Pathways
- L'effet Warburg
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