ANKRD15 anticorps

N° du produit ABIN5696934

Détail du produit anti-ANKRD15 anticorps

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANKRD15 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Immunogène: KN motif and ankyrin repeat domains 1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab04463( KANK1 Antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur ANKRD15

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Autre désignation: KANK1 (ANKRD15 Produits)

Synonymes: anticorps ANKRD15, anticorps CPSQ2, anticorps KANK, anticorps A930031B09Rik, anticorps AU015049, anticorps AW121052, anticorps Ankrd15, anticorps D330024H06Rik, anticorps mKIAA0172, anticorps KANK1, anticorps ankrd15, anticorps kank1.2, anticorps DMRT1, anticorps KN motif and ankyrin repeat domains 1, anticorps KN motif and ankyrin repeat domains 1 L homeolog, anticorps doublesex and mab-3 related transcription factor 1, anticorps KANK1, anticorps Kank1, anticorps kank1.L, anticorps DMRT1

Sujet: Synonyms:ANKRD15, KANK, KIAA0172 Background:Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity, the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia, the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading, the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.

Poids moléculaire: 75-85 kDa,30 kDa

ID gène: 23189

UniProt: Q14678

Pathways: Regulation of Actin Filament Polymerization