CDK5RAP3 anticorps
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- Antigène Voir toutes CDK5RAP3 Anticorps
- CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDK5RAP3 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Immunogène
- CDK5 regulatory subunit associated protein 3
- Isotype
- IgG
- Top Product
- Discover our top product CDK5RAP3 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab01560(CDK5RAP3 antibody) at dilution of 1:2000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))
- Autre désignation
- CDK5RAP3 (CDK5RAP3 Produits)
- Synonymes
- anticorps cdkrap3, anticorps fb33h04, anticorps fc09c05, anticorps id:ibd2920, anticorps wu:fb33h04, anticorps wu:fc09c05, anticorps zgc:86863, anticorps CDK5RAP3, anticorps cdk5rap3, anticorps MGC82350, anticorps C53, anticorps HSF-27, anticorps IC53, anticorps LZAP, anticorps MST016, anticorps OK/SW-cl.114, anticorps PP1553, anticorps 1810007E24Rik, anticorps BC002318, anticorps C81486, anticorps CDK5 regulatory subunit associated protein 3, anticorps CDK5 regulatory subunit associated protein 3 L homeolog, anticorps cdk5rap3, anticorps CDK5RAP3, anticorps cdk5rap3.L, anticorps Cdk5rap3
- Sujet
- Synonyms:IC53, Background:Probable tumor suppressor initially identified as a CDK5R1 interactor controlling cell proliferation(PubMed:12054757, PubMed:12737517). Negatively regulates NF-kappa-B-mediated gene transcription through the control of RELA phosphorylation(PubMed:17785205, PubMed:20228063). Also regulates mitotic G2/M transition checkpoint and mitotic G2 DNA damage checkpoint(PubMed:15790566, PubMed:19223857). Through its interaction with CDKN2A/ARF and MDM2 may induce MDM2-dependent p53/TP53 ubiquitination, stabilization and activation in the nucleus, thereby promoting G1 cell cycle arrest and inhibition of cell proliferation(PubMed:16173922). May play a role in the unfolded protein response, mediating the ufmylation of multiple proteins in response to endoplasmic reticulum stress(PubMed:23152784). May also play a role in the rupture of the nuclear envelope during apoptosis(PubMed:23478299). May regulate MAPK14 activity by regulating its dephosphorylation by PPM1D/WIP1(PubMed:21283629). (Microbial infection) May be negatively regulated by hepatitis B virus large envelope protein mutant pre-s2 to promote mitotic entry.
- Poids moléculaire
- 65 kDa
- ID gène
- 80279
- UniProt
- Q96JB5
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