SNX6 anticorps
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- Antigène Voir toutes SNX6 Anticorps
- SNX6 (Sorting Nexin 6 (SNX6))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SNX6 est non-conjugé
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Immunogène
- sorting nexin 6
- Isotype
- IgG
- Top Product
- Discover our top product SNX6 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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RAW 264.7 cells were subjected to SDS PAGE followed by western blot with FNab08095( SNX6 Antibody) at dilution of 1:600
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- SNX6 (Sorting Nexin 6 (SNX6))
- Autre désignation
- SNX6 (SNX6 Produits)
- Synonymes
- anticorps MGC75952, anticorps MGC80251, anticorps im:7146294, anticorps wu:fa55b10, anticorps zgc:110798, anticorps MSTP010, anticorps TFAF2, anticorps 2010006G21Rik, anticorps 2610032J07Rik, anticorps 2810425K19Rik, anticorps AU018928, anticorps C85963, anticorps sorting nexin 6, anticorps sorting nexin 6 L homeolog, anticorps snx6, anticorps snx6.L, anticorps SNX6, anticorps Snx6
- Sujet
- Synonyms: Background:Involved in several stages of intracellular trafficking. Interacts with membranes phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 4,5-bisphosphate(Probable). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex(PubMed:19935774). The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier(ETC)(Probable). Does not have in vitro vesicle-to-membrane remodeling activity(PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptor IGF2R(PubMed:17148574). May function as link between transport vesicles and dynactin(Probable). Negatively regulates retrograde transport of BACE1 from the cell surface to the trans-Golgi network(PubMed:20354142). Involved in E-cadherin sorting and degradation, inhibits PIP5K1C isoform 3-mediated E-cadherin degradation(PubMed:24610942). In association with GIT1 involved in EGFR degradation. Promotes lysosomal degradation of CDKN1B(By similarity). May contribute to transcription regulation(Probable).
- ID gène
- 58533
- UniProt
- Q9UNH7
- Pathways
- EGFR Signaling Pathway
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