Sphingomyelin Synthase 1 anticorps

N° du produit ABIN5698483

Détail du produit anti-Sphingomyelin Synthase 1 anticorps

Antigène: Sphingomyelin Synthase 1 (SGMS1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sphingomyelin Synthase 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogène: sphingomyelin synthase 1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

human heart tissue were subjected to SDS PAGE followed by western blot with FNab07811(SGMS1 antibody) at dilution of 1:300

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur Sphingomyelin Synthase 1

Antigène: Sphingomyelin Synthase 1 (SGMS1)

Autre désignation: SGMS1 (SGMS1 Produits)

Synonymes: anticorps MGC81436, anticorps TMEM23, anticorps MOB, anticorps MOB1, anticorps SMS1, anticorps hmob33, anticorps 9530058O11Rik, anticorps AI841905, anticorps C80702, anticorps Mob, anticorps Sms1, anticorps Sor1, anticorps Tmem23, anticorps sphingomyelin synthase 1, anticorps sphingomyelin synthase 1 S homeolog, anticorps phosphatidylcholine:ceramide cholinephosphotransferase 1, anticorps SGMS1, anticorps sgms1.S, anticorps LOC100013212, anticorps Sgms1

Sujet: Synonyms:MOB, SMS1, TMEM23 Background:Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

ID gène: 259230

UniProt: Q86VZ5

Pathways: Cellular Response to Molecule of Bacterial Origin