PLAG1 anticorps

N° du produit ABIN5698797

Détail du produit anti-PLAG1 anticorps

Antigène: PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAG1 est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: pleiomorphic adenoma gene 1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur PLAG1

Antigène: PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

Autre désignation: PLAG1 (PLAG1 Produits)

Synonymes: anticorps PLAG1, anticorps MGC152687, anticorps PSA, anticorps SGPA, anticorps ZNF912, anticorps PLAG1 zinc finger, anticorps pleiomorphic adenoma gene 1, anticorps PLAG1, anticorps plag1, anticorps Plag1

Sujet: Synonyms: Background:Transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia.

ID gène: 5324

UniProt: Q6DJT9