CACNA1S anticorps

N° du produit ABIN5700411

Détail du produit anti-CACNA1S anticorps

Antigène: CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CACNA1S est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Immunogène: calcium channel, voltage-dependent, L type, alpha 1S subunit

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab01173(CACNA1S antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur CACNA1S

Antigène: CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))

Autre désignation: CACNA1S (CACNA1S Produits)

Synonymes: anticorps CACNA1S, anticorps cav1.1, anticorps ca(v)1.1, anticorps CACNL1A3, anticorps CCHL1A3, anticorps Cav1.1, anticorps HOKPP, anticorps HOKPP1, anticorps MHS5, anticorps TTPP1, anticorps hypoPP, anticorps AW493108, anticorps Cchl1a3, anticorps fmd, anticorps mdg, anticorps sj, anticorps caV1.1, anticorps calcium voltage-gated channel subunit alpha1 S, anticorps calcium channel, voltage-dependent, L type, alpha 1S subunit S homeolog, anticorps calcium channel, voltage-dependent, L type, alpha 1S subunit, anticorps CACNA1S, anticorps cacna1s.S, anticorps Cacna1s

Sujet: Synonyms:CACH1, CACN1, CACNL1A3 Background:Voltage-sensitive calcium channels(VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1S gives rise to L-type calcium currents. Long-lasting(L-type) calcium channels belong to the 'high-voltage activated'(HVA) group. They are blocked by dihydropyridines(DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA(omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA(omega-CTx-GVIA) and omega-agatoxin-IVA(omega-Aga-IVA). Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle.

Poids moléculaire: 200-220 kDa

ID gène: 779

UniProt: Q13698

Pathways: Skeletal Muscle Fiber Development