COPS3 anticorps

N° du produit ABIN5700531

Détail du produit anti-COPS3 anticorps

Antigène: COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COPS3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogène: COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab01871(COPS3 antibody) at dilution of 1:500

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur COPS3

Antigène: COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))

Autre désignation: COPS3 (COPS3 Produits)

Synonymes: anticorps CG18332, anticorps CH3, anticorps Csn3, anticorps DCH3, anticorps Dch3, anticorps Dmel\\CG18332, anticorps FBgn0027055, anticorps dCSN3, anticorps COPS3, anticorps CSN3, anticorps DKFZp468P1922, anticorps Sgn3, anticorps wu:fc32a02, anticorps wu:fk59f01, anticorps zgc:111903, anticorps zgc:55643, anticorps zgc:77615, anticorps CONSTITUTIVE PHOTOMORPHOGENIC 13, anticorps COP9 SIGNALOSOME SUBUNIT 3, anticorps F18O22.40, anticorps F18O22_40, anticorps FUS11, anticorps FUSCA 11, anticorps SGN3, anticorps csn3, anticorps COP9 signalosome subunit 3, anticorps Proteasome component (PCI) domain protein, anticorps COP9 signalosome subunit 3 L homeolog, anticorps COP9 signalosome complex subunit 3, anticorps CSN3, anticorps cops3, anticorps COPS3, anticorps Cops3, anticorps COP13, anticorps cops3.L, anticorps csn-3

Sujet: Synonyms:CSN3 Background:Component of the COP9 signalosome complex(CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin(Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

Poids moléculaire: 48 kDa

ID gène: 8533

UniProt: Q9UNS2

Pathways: Cycle Cellulaire