DIS3L2 anticorps

N° du produit ABIN5700727

Détail du produit anti-DIS3L2 anticorps

Antigène: DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DIS3L2 est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: DIS3 mitotic control homolog (S. cerevisiae)-like 2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur DIS3L2

Antigène: DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

Autre désignation: DIS3L2 (DIS3L2 Produits)

Synonymes: anticorps RGD1560168, anticorps DIS3L2, anticorps DKFZp469O0522, anticorps FAM6A, anticorps PRLMNS, anticorps hDIS3L2, anticorps 4930429A22Rik, anticorps 8030493P09Rik, anticorps DIS3-like 3'-5' exoribonuclease 2, anticorps DIS3 like 3'-5' exoribonuclease 2, anticorps DIS3-like exonuclease 2, anticorps Dis3l2, anticorps DIS3L2, anticorps LOC100344728

Sujet: Synonyms:FAM6A Background:3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem(ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.

Poids moléculaire: 65 kDa, 99 kDaa

ID gène: 129563

UniProt: Q8IYB7

Pathways: Stem Cell Maintenance