KAT5 anticorps

N° du produit ABIN5701767

Détail du produit anti-KAT5 anticorps

Antigène: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KAT5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogène: K(lysine) acetyltransferase 5

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

PC-3 cells were subjected to SDS PAGE followed by western blot with FNab04468(KAT5 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur KAT5

Antigène: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Autre désignation: KAT5 (KAT5 Produits)

Synonymes: anticorps 6121, anticorps CG6121, anticorps DmEG0007.7, anticorps Dmel/TIP60, anticorps Dmel\\CG6121, anticorps Dmel\\TIP60, anticorps EG0007.7, anticorps EG:EG0007.7, anticorps TIP60, anticorps dTIP60, anticorps dTip60, anticorps dmHAG405, anticorps im:6908768, anticorps wu:fb55b08, anticorps zgc:110752, anticorps ESA1, anticorps HTATIP, anticorps HTATIP1, anticorps PLIP, anticorps TIP, anticorps ZC2HC5, anticorps cPLA2, anticorps AI839539, anticorps CPLA2, anticorps Htatip, anticorps Htatip1, anticorps Tip55, anticorps Tip60, anticorps K(lysine) acetyltransferase 5a, anticorps lysine acetyltransferase 5, anticorps Tat interactive protein 60kDa, anticorps histone acetyltransferase Tip60, anticorps tip60, putative, anticorps K(lysine) acetyltransferase 5b, anticorps K(lysine) acetyltransferase 5, anticorps kat5a, anticorps KAT5, anticorps Tip60, anticorps LOC413101, anticorps LOC5579231, anticorps Smp_053140, anticorps kat5b, anticorps Kat5

Sujet: Synonyms:HTATIP, TIP60 Background:Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation. Relieves NR1D2-mediated inhibition of APOC3 expression by acetylating NR1D2. Promotes FOXP3 acetylation and positively regulates its transcriptional repressor activity(PubMed:17360565).

Poids moléculaire: 55-60 kDa

ID gène: 10524

UniProt: Q92993

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway