MLXIP anticorps

N° du produit ABIN5701831

Détail du produit anti-MLXIP anticorps

Antigène: MLXIP (MLX Interacting Protein (MLXIP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLXIP est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogène: MLX interacting protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

K-562 cells were subjected to SDS PAGE followed by western blot with FNab05223(MLXIP antibody) at dilution of 1:500

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur MLXIP

Antigène: MLXIP (MLX Interacting Protein (MLXIP))

Autre désignation: MLXIP (MLXIP Produits)

Synonymes: anticorps MGC83884, anticorps si:ch211-110p13.4, anticorps MIR, anticorps MONDOA, anticorps bHLHe36, anticorps AW228700, anticorps B930074I24, anticorps Mir, anticorps mKIAA0867, anticorps RGD1560774, anticorps MLX interacting protein, anticorps MLX interacting protein L homeolog, anticorps MLXIP, anticorps mlxip.L, anticorps mlxip, anticorps Mlxip

Sujet: Synonyms:BHLHE36, KIAA0867, MIR, MONDOA Background:Mlx-interacting protein(MLXIP), after forming heterodimers with MLX, can bind to and then activate transcription from CACGTG E boxes. The N terminus of MLXIP acts as a CRM1-dependent nuclear export signal and contribute to the cytoplasmic localization of the complex, and as a binding site for 13 protein. the C terminus contains a cytoplasmic localization signal and mediates protein-protein interaction of MONDOA and MLX. The complex play a role in transcriptional activation of glycolytic target genes and glucose-responsive gene regulation. This antibody could recognize isoform1(~110kd) and isoform3(~69kd) of MLXIP. A specific MLXIP of approximately 130 kDa was detected. It demonstrates that MLXIP associated specifically with Mlx in the cytoplasm (PMID: 11073985).

Poids moléculaire: 130 kDa

ID gène: 22877

UniProt: Q9HAP2