PSMF1 anticorps

N° du produit ABIN5703122

Détail du produit anti-PSMF1 anticorps

Antigène: PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMF1 est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: proteasome (prosome, macropain) inhibitor subunit 1 (PI31)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur PSMF1

Antigène: PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

Autre désignation: PSMF1 (PSMF1 Produits)

Synonymes: anticorps PI31, anticorps AW048666, anticorps BC012260, anticorps zgc:92785, anticorps proteasome inhibitor subunit 1, anticorps proteasome (prosome, macropain) inhibitor subunit 1, anticorps PSMF1, anticorps Psmf1, anticorps psmf1

Sujet: Synonyms: Background:The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.

ID gène: 9491

UniProt: Q92530

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA