F2RL1 anticorps
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- Antigène Voir toutes F2RL1 Anticorps
- F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp F2RL1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Immunogène
- coagulation factor II (thrombin) receptor-like 1
- Isotype
- IgG
- Top Product
- Discover our top product F2RL1 Anticorps primaire
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- Indications d'application
- WB : 1:200-1:2000
- Commentaires
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COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab06145( F2RL1 Antibody) at dilution of 1:600
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
- Autre désignation
- PAR2 (F2RL1 Produits)
- Synonymes
- anticorps par2, anticorps GPR11, anticorps PAR2, anticorps Gpcr11, anticorps PAR-2, anticorps Par2, anticorps Par-2, anticorps Proteinase-activated receptor 2, anticorps F2R like trypsin receptor 1, anticorps coagulation factor II (thrombin) receptor-like 1, anticorps par2, anticorps F2RL1, anticorps F2rl1
- Sujet
- Synonyms:F2RL1, G protein coupled receptor 11, GPR11, PAR 2, PAR2, Thrombin receptor like 1 Background:Proteinase-activated receptors(PARs) are G protein-coupled receptors activated through cleavage of their N-termini by mainly serine proteases. The family of PARs include four members: PAR1, PAR2, PAR3 and PAR4. PAR2, also known as F2RL1, is expressed in epithelial cells(e.g., lung, gastrointestinal tract), endothelial cells, smooth muscle cells, fibroblasts, nerves, and some immune and inflammatory cells. PAR2 knockout mice and PAR2 agonists and antagonists have implicated PAR2 as a promising target in inflammatory conditions, respiratory, gastrointestinal, metabolic, cardiovascular, and neurological dysfunction, and cancers.(PMID:23895492)
- Poids moléculaire
- 50kDa
- UniProt
- P55085
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
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