GPSM1 anticorps

N° du produit ABIN5703533

Détail du produit anti-GPSM1 anticorps

Antigène: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPSM1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogène: G-protein signaling modulator 1 (AGS3-like, C. elegans)

Isotype: IgG

Information d'application

Indications d'application: WB :1:200-1:2000,IF:1:10-1:100,IHC:1:20-1:200

Commentaires:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab00221(GPSM1 antibody) at dilution of 1:600

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur GPSM1

Antigène: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Autre désignation: AGS3 (GPSM1 Produits)

Synonymes: anticorps 1810037C22Rik, anticorps AW107933, anticorps Ags3, anticorps AGS3, anticorps ags3, anticorps gpsm1, anticorps G-protein signalling modulator 1 (AGS3-like, C. elegans), anticorps G-protein signaling modulator 1, anticorps G protein signaling modulator 1, anticorps G-protein signaling modulator 1 L homeolog, anticorps Gpsm1, anticorps GPSM1, anticorps gpsm1.L

Sujet: Synonyms:AGS3, DKFZp727I051, GPSM1 Background:GPSM1, also named as AGS3, is a receptor-independent G protein activator that has been implicated in multiple biological events such as brain development, neuroplasticity and addiction, cardiac function, Golgi structure/function, macroautophagy and metabolism. It contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory(GPR) motifs in its C-terminal half. It has been shown that AGS3 could regulate the orientation of the mitotic spindle, cAMP production, membrane protein transport, and asymmetric cell division by binding preferentially to inactive Gai/o subunits complexed with guanine dinucleotide phosphate(GDP) at multiple G-protein regulatory or GoLoco motif repeats. It also plays an important anti-apoptotic role through enhancing the phosphorylation of cyclic AMP response element-binding protein(p-CREB).

Poids moléculaire: 72kDa

UniProt: Q86YR5

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling