TRIM33 anticorps

N° du produit ABIN5704459

Détail du produit anti-TRIM33 anticorps

Antigène: TRIM33 (Tripartite Motif Containing 33 (TRIM33))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM33 est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: tripartite motif-containing 33

Isotype: IgG

Information d'application

Indications d'application: WB:1:200-1:2000

Commentaires:

COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab08981(TRIM33 antibody) at dilution of 1:500

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur TRIM33

Antigène: TRIM33 (Tripartite Motif Containing 33 (TRIM33))

Autre désignation: TRIM33 (TRIM33 Produits)

Synonymes: anticorps TRIM33, anticorps ptc7, anticorps rfg7, anticorps tf1g, anticorps tif1g, anticorps tifgamma, anticorps MGC146665, anticorps tif1gamma, anticorps ECTO, anticorps PTC7, anticorps RFG7, anticorps TF1G, anticorps TIF1G, anticorps TIF1GAMMA, anticorps TIFGAMMA, anticorps ecto, anticorps 8030451N04Rik, anticorps AI413936, anticorps Ecto, anticorps Tif1g, anticorps ectodermin, anticorps mKIAA1113, anticorps cb1085, anticorps id:ibd2175, anticorps mon, anticorps wu:fc17f10, anticorps zgc:136680, anticorps tripartite motif containing 33, anticorps tripartite motif containing 33 L homeolog, anticorps tripartite motif-containing 33, anticorps TRIM33, anticorps trim33, anticorps trim33.L, anticorps Trim33

Sujet: Synonyms:Ectodermin homolog, FLJ32925, KIAA1113, Protein Rfg7, PTC7, RET fused gene 7 protein, RFG7, TF1G, TIF1 gamma, TIF1G, TIF1GAMMA, TIFGAMMA, TRIM33, tripartite motif containing 33 Background:Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor(By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade(Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).

Poids moléculaire: 72kDa

ID gène: 51592

UniProt: Q9UPN9