STK36 anticorps

N° du produit ABIN5704879

Détail du produit anti-STK36 anticorps

Antigène: STK36 (serine/threonine Kinase 36 (STK36))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STK36 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Immunogène: serine/threonine kinase 36, fused homolog (Drosophila)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab08335(STK36 antibody) at dilution of 1:300

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur STK36

Antigène: STK36 (serine/threonine Kinase 36 (STK36))

Autre désignation: STK36 (STK36 Produits)

Synonymes: anticorps FU, anticorps fused-like, anticorps 1700112N14Rik, anticorps B930045J24, anticorps Fused, anticorps mKIAA1278, anticorps fu, anticorps si:dkey-180i4.3, anticorps zgc:152944, anticorps serine/threonine kinase 36, anticorps serine/threonine kinase 36 (fused homolog, Drosophila), anticorps STK36, anticorps Stk36, anticorps stk36

Sujet: Synonyms:KIAA1278 Background:Serine/threonine protein kinase which plays an important role in the sonic hedgehog(Shh) pathway by regulating the activity of GLI transcription factors(PubMed:10806483). Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization(PubMed:10806483). GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur(PubMed:10806483). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function(By similarity). Essential for construction of the central pair apparatus of motile cilia.

ID gène: 27148

UniProt: Q9NRP7