RSPO2 anticorps

N° du produit ABIN5705242

Détail du produit anti-RSPO2 anticorps

Antigène: RSPO2 (R-Spondin 2 (RSPO2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RSPO2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Immunogène: R-spondin 2 homolog (Xenopus laevis)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur RSPO2

Antigène: RSPO2 (R-Spondin 2 (RSPO2))

Autre désignation: RSPO2 (RSPO2 Produits)

Synonymes: anticorps RGD1562331, anticorps CRISTIN2, anticorps 2610028F08Rik, anticorps AA673245, anticorps D430027K22, anticorps ftls, anticorps R-spondin 2, anticorps R-spondin 2 L homeolog, anticorps Rspo2, anticorps rspo2.L, anticorps rspo2, anticorps RSPO2

Sujet: Synonyms:CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2 Background:Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6(LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.

ID gène: 340419

UniProt: Q6UXX9