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Betacellulin anticorps

BTC Reactivité: Souris, Rat WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5708196
  • Antigène Voir toutes Betacellulin (BTC) Anticorps
    Betacellulin (BTC)
    Reactivité
    • 46
    • 33
    • 12
    • 2
    • 1
    Souris, Rat
    Hôte
    • 62
    • 6
    • 1
    • 1
    Lapin
    Clonalité
    • 65
    • 5
    Polyclonal
    Conjugué
    • 33
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Betacellulin est non-conjugé
    Application
    • 62
    • 20
    • 16
    • 13
    • 13
    • 9
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity purified
    Immunogène
    A rat partial recombinant protein corresponding to amino acids D32-A177 was used as the immunogen for the Betacellulin antibody.
    Isotype
    IgG
    Top Product
    Discover our top product BTC Anticorps primaire
  • Indications d'application
    Optimal dilution of the Betacellulin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (recombinant rat protein) (BSA-free format available)
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    After reconstitution, the Betacellulin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène
    Betacellulin (BTC)
    Autre désignation
    Betacellulin / BTC (BTC Produits)
    Synonymes
    anticorps BTC, anticorps LOC100228121, anticorps probetacellulin, anticorps Bcn, anticorps betacellulin, anticorps betacellulin, epidermal growth factor family member, anticorps BTC, anticorps LOC100228121, anticorps Btc
    Sujet
    Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.
    UniProt
    Q9JJM4
    Pathways
    Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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