Betacellulin anticorps
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- Antigène Voir toutes Betacellulin (BTC) Anticorps
- Betacellulin (BTC)
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Reactivité
- Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Betacellulin est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity purified
- Immunogène
- A rat partial recombinant protein corresponding to amino acids D32-A177 was used as the immunogen for the Betacellulin antibody.
- Isotype
- IgG
- Top Product
- Discover our top product BTC Anticorps primaire
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- Indications d'application
- Optimal dilution of the Betacellulin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (recombinant rat protein) (BSA-free format available)
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the Betacellulin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- Betacellulin (BTC)
- Autre désignation
- Betacellulin / BTC (BTC Produits)
- Synonymes
- anticorps BTC, anticorps LOC100228121, anticorps probetacellulin, anticorps Bcn, anticorps betacellulin, anticorps betacellulin, epidermal growth factor family member, anticorps BTC, anticorps LOC100228121, anticorps Btc
- Sujet
- Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.
- UniProt
- Q9JJM4
- Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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