CD44 anticorps

N° du produit ABIN5708207

Détail du produit anti-CD44 anticorps

Antigène: CD44

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD44 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogène: A recombinant human partial protein corresponding to amino acids Q21-H259 was used as the immunogen for the CD44 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CD44 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CD44 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur CD44

Antigène: CD44

Autre désignation: CD44 (CD44 Produits)

Synonymes: anticorps CDW44, anticorps CSPG8, anticorps ECMR-III, anticorps HCELL, anticorps HUTCH-I, anticorps IN, anticorps LHR, anticorps MC56, anticorps MDU2, anticorps MDU3, anticorps MIC4, anticorps Pgp1, anticorps AU023126, anticorps AW121933, anticorps AW146109, anticorps HERMES, anticorps Ly-24, anticorps Pgp-1, anticorps CD44A, anticorps METAA, anticorps RHAMM, anticorps XCD44, anticorps cd44, anticorps cdw44, anticorps cspg8, anticorps ecmr-iii, anticorps hcell, anticorps lhr, anticorps mc56, anticorps mdu2, anticorps mdu3, anticorps mic4, anticorps mutch-i, anticorps pgp1, anticorps CD44 molecule (Indian blood group), anticorps syndecan 4, anticorps CD44 antigen, anticorps CD44 molecule (Indian blood group) S homeolog, anticorps CD44, anticorps SDC4, anticorps Cd44, anticorps cd44.S

Sujet: CD44 is also known as LHR or MC56. The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling