STAM anticorps

N° du produit ABIN5708332

Détail du produit anti-STAM anticorps

Antigène: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAM est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids F9-Q254 was used as the immunogen for the STAM1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the STAM1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the STAM1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur STAM

Antigène: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Autre désignation: STAM1 (STAM Produits)

Synonymes: anticorps STAM-1, anticorps STAM1, anticorps wu:fv75b10, anticorps zgc:55725, anticorps RGD1564499, anticorps signal transducing adaptor molecule, anticorps signal transducing adapter molecule 1, anticorps Signal transducing adapter molecule 1, anticorps signal transducing adaptor molecule (SH3 domain and ITAM motif) 1, anticorps STAM, anticorps CpipJ_CPIJ003516, anticorps Tsp_03939, anticorps stam-1, anticorps Stam, anticorps stam

Sujet: Signal transducing adapter molecule 1 is a protein that in humans is encoded by the STAM gene. This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene.

UniProt: Q92783

Pathways: EGFR Signaling Pathway, EGFR Downregulation