CBX3 anticorps

N° du produit ABIN5708343

Détail du produit anti-CBX3 anticorps

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogène: A recombinant human partial protein corresponding to amino acids A2-Q183 was used as the immunogen for the CBX3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CBX3 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CBX3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur CBX3

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Autre désignation: HP1 gamma / Heterochromatin protein-1 gamma / CBX3 (CBX3 Produits)

Synonymes: anticorps HECH, anticorps HP1-GAMMA, anticorps HP1Hs-gamma, anticorps Hp1-gamma, anticorps HP1g, anticorps M32, anticorps cbx3, anticorps cbx3a, anticorps xhp1g, anticorps wu:fb61b02, anticorps zgc:153397, anticorps chromobox 3, anticorps chromobox 3 L homeolog, anticorps chromobox protein homolog 3 pseudogene, anticorps chromobox homolog 3a (HP1 gamma homolog, Drosophila), anticorps CBX3, anticorps Cbx3, anticorps cbx3.L, anticorps LOC100355282, anticorps cbx3a

Sujet: Chromobox protein homolog 3 is a protein that is encoded by the CBX3 gene in humans. At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

UniProt: Q13185