IGF2R anticorps

N° du produit ABIN5708375

Détail du produit anti-IGF2R anticorps

Antigène: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGF2R est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids F424-R529 was used as the immunogen for the M6PR antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the M6PR antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL, IHC (FFPE): 1-2 μg/mL, Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the M6PR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur IGF2R

Antigène: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Autre désignation: M6PR / IGF2R (IGF2R Produits)

Synonymes: anticorps CD222, anticorps CIMPR, anticorps M6P-R, anticorps MPR1, anticorps MPRI, anticorps AI661837, anticorps CI-MPR, anticorps M6P/IGF2R, anticorps Mpr300, anticorps mpri, anticorps cd222, anticorps cimpr, anticorps m6p-r, anticorps insulin like growth factor 2 receptor, anticorps insulin-like growth factor 2 receptor, anticorps IGF2R, anticorps Igf2r, anticorps igf2r

Sujet: Insulin-like growth factor 2 receptor, also called IGF2R, I-MPR and M6PR (mannose 6-phosphate receptor) is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

UniProt: P11717