SCNN1A anticorps (Extracellular Domain)

N° du produit ABIN571620

Détail du produit anti-SCNN1A anticorps

Antigène: SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))

Épitope: Extracellular Domain

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCNN1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Specific for SCNN1A.

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from the extracellular domain of human SCNN1A conjugated to an immunogenic carrier protein was used as the antigen.

Information d'application

Indications d'application: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur SCNN1A

Antigène: SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))

Autre désignation: SCNN1A (SCNN1A Produits)

Synonymes: anticorps BESC2, anticorps ENaCa, anticorps ENaCalpha, anticorps SCNEA, anticorps SCNN1, anticorps ENaC, anticorps Scnn1, anticorps mENaC, anticorps SCNN1A, anticorps alphaxENaC, anticorps besc2, anticorps enaca, anticorps scnn1, anticorps ENAC, anticorps sodium channel epithelial 1 alpha subunit, anticorps sodium channel, nonvoltage-gated 1 alpha, anticorps sodium channel, non voltage gated 1 alpha subunit L homeolog, anticorps Scnn1a, anticorps SCNN1A, anticorps scnn1a.L

Sujet: FUNCTION: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. SUBCELLULAR LOCATION: Apical cell membrane, Multi-pass membrane protein. Note: Apical membrane of epithelial cells. TISSUE SPECIFICITY: Highly expressed in kidney and lung. Detected at intermediate levels in pancreas and liver, and at low levels in heart and placenta. Isoform 1 and isoform 2 predominate in all tissues. Expression of isoform 3, isoform 4 and isoform 5 is very low or not detectable, except in lung and heart. INDUCTION: By aldosterone.,SCNN Channels,Epithelial a(+) channel subunit alpha, alpha-ENaC, Nonvoltage-gated sodium channel 1 subunit alpha, alpha-NaCH, SCNN1, ENaCalpha, Alpha-ENaC