Annexin V anticorps (Biotin)

N° du produit ABIN576509

Détail du produit anti-Annexin V anticorps (Biotin)

Antigène: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Annexin V est conjugé à/à la Biotin

Application: ELISA, Flow Cytometry (FACS)

Specificité: Recognizes human Annexin V, a phospholipid binding protein which binds with high affinity and selectivity to phosphatidylserine (PS), in the presence of calcium. The translocation of PS from the cytosolic leaflet to the outer leaflet of the plasma membrane, due to a loss in plasma membrane asymmetry during apoptosis, acts as an in vivo signal for the removal of the dying cell by phagocytosis. Detection of PS using Annexin V therefore provides a reliable diagnostic tool for the indication of early programmed cell death. Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V, are associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc). Clone VAA-33 has been reported to work in western blotting applications.

Purification: Protein G purified

Immunogène: Recombinant Annexin V.

Type of Immunogen: Recombinant protein

Isotype: IgG2a

Information d'application

Indications d'application: Approved: ELISA, Flo

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline, 1 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur Annexin V

Antigène: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Autre désignation: ANXA5 / Annexin V (ANXA5 Produits)

Synonymes: anticorps anx, anticorps anx5, anticorps ANX V, anticorps anxa5, anticorps cb989, anticorps wu:fa98f06, anticorps wu:fj10f10, anticorps MGC89158, anticorps ANX5, anticorps ENX2, anticorps PP4, anticorps RPRGL3, anticorps Anx5, anticorps R74653, anticorps LC5, anticorps enx2, anticorps annexin A5, anticorps annexin A5b, anticorps Annexin A5, anticorps annexin A5 L homeolog, anticorps ANXA5, anticorps anxa5b, anticorps anxa5, anticorps Anxa5, anticorps anxa5.L

Sujet: Name/Gene ID: ANXA5

Synonyms: ANXA5, ANX5, Anchorin CII, Calphobindin I, CBP-I, ENX2, PP4, RPRGL3, Lipocortin V, Thromboplastin inhibitor, VAC-alpha, Vascular anticoagulant-alpha, PAP-I, Annexin A5, Annexin V, Annexin-5, Endonexin II

ID gène: 308

UniProt: P08758

Pathways: Apoptose