MTOR anticorps (pSer2448)

N° du produit ABIN601927

Cet anticorps Lapin Polyclonal détecte spécifiquement MTOR dans IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Mouton, Boeuf (Vache), Chien, Poulet, Cheval, Lapin et Singe.

Aperçu rapide pour MTOR anticorps (pSer2448) (ABIN601927)

Antigène: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Reactivité: Humain, Souris, Rat, Mouton, Boeuf (Vache), Chien, Poulet, Cheval, Lapin, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTOR est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-MTOR anticorps

Épitope: pSer2448

Specificité: Recognizes human mTOR when phosphorylated at serine 2448. Species cross-reactivity: mouse, rat.

Purification: Immunoaffinity purified

Immunogène: Synthetic phosphopeptide corresponding to human mTOR around the phosphorylation site of serine 2448 (T-D-SP-Y-S).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: IHC (1:50 - 1:100)

Usage: Suitable for use in Immunohistochemistry: 1:50-1:100.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Aliquot to Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Détails sur MTOR

Antigène: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Autre désignation: MTOR

Sujet: Name/Gene ID: MTOR
Subfamily: PI3/PI4
Family: Protein Kinase

Synonyms: MTOR, FRAP1, FRAP2, FRAP, Mammalian target of rapamycin, RAFT1, Rapamycin and FKBP12 target 1, RAPT1, Rapamycin target protein 1

ID gène: 2475

UniProt: P42345

Pathways: Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, L'effet Warburg