p53 anticorps (FITC)

N° du produit ABIN610211

L’anticorps Souris Monoclonal anti-p53 a été validé pour WB, IHC et FACS. Il convient pour détecter p53 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Hamster et Poulet. Il y a 2+ publications disponibles.

Aperçu rapide pour p53 anticorps (FITC) (ABIN610211)

Antigène: p53 (TP53) (Tumor Protein P53 (TP53))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Hamster, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp p53 est conjugé à/à la FITC

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: PAb240

Détail du produit anti-p53 anticorps (FITC)

Specificité: Denaturization resistant p53 epitope between amino acids 156-214. It is cross reactive with human, mouse, hamster, rat, bovine and chicken tissues.

Purification: Protein A purified

Immunogène: Murine p53 fragment expressed in E. coli.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Approved: Flo, IHC, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze. Product is photosensitive and should be protected from light.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze. Protect from light.

Références pour anticorps anti-p53 (FITC) (ABIN610211)

Tomicic, Thust, Kaina: "Ganciclovir-induced apoptosis in HSV-1 thymidine kinase expressing cells: critical role of DNA breaks, Bcl-2 decline and caspase-9 activation." dans: Oncogene, Vol. 21, Issue 14, pp. 2141-53, (2002) (PubMed).

Jiang, Clark: "Involvement of Bik, a proapoptotic member of the Bcl-2 family, in surface IgM-mediated B cell apoptosis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 10, pp. 6025-33, (2001) (PubMed).

Détails sur p53

Antigène: p53 (TP53) (Tumor Protein P53 (TP53))

Autre désignation: TP53 / p53

Sujet: Name/Gene ID: TP53
Family: P53

Synonyms: TP53, BCC7, Cellular tumor antigen p53, p53, TRP53, p53 tumor suppressor, Phosphoprotein p53, Antigen NY-CO-13, Tumor protein p53, Tumor suppressor p53, LFS1

ID gène: 7157

UniProt: P04637

Pathways: Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg