FYN anticorps (pSer21)

N° du produit ABIN6136086

Cet anticorps Lapin Polyclonal détecte spécifiquement FYN dans WB. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour FYN anticorps (pSer21) (ABIN6136086)

Antigène: FYN (FYN Oncogene Related To SRC, FGR, YES (FYN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FYN est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FYN anticorps

Épitope: pSer21

Séquence: DGSLN

Réactivité croisée: Humain

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A synthetic phosphorylated peptide around S21 of human Phospho-Fyn-S21 (NP_002028.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-FYN (ABIN6136086)

Nakanishi, Menju, Nishikawa, Takahashi, Miyata, Shikuma, Sowa, Imamura, Hamaji, Motoyama, Hijiya, Aoyama, Sato, Chen-Yoshikawa, Sonobe, Date: "The synergistic role of ATP-dependent drug efflux pump and focal adhesion signaling pathways in vinorelbine resistance in lung cancer." dans: Cancer medicine, Vol. 7, Issue 2, pp. 408-419, (2018) (PubMed).

Détails sur FYN

Antigène: FYN (FYN Oncogene Related To SRC, FGR, YES (FYN))

Autre désignation: FYN

Sujet: This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.,FYN,SLK,SYN,p59-FYN,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Cell Adhesion,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Protein phosphorylation,FYN

Poids moléculaire: 54 kDa/60 kDa

ID gène: 2534

UniProt: P06241

Pathways: Signalistation JAK/STAT, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Activated T Cell Proliferation, Thromboxane A2 Receptor Signaling