Adenylosuccinate Lyase anticorps (AA 1-310)

N° du produit ABIN6136602

Détail du produit anti-Adenylosuccinate Lyase anticorps

Antigène: Adenylosuccinate Lyase (ADSL)

Épitope: AA 1-310

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adenylosuccinate Lyase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Séquence: MAAGGDHGSP DSYRSPLASR YASPEMCFVF SDRYKFRTWR QLWLWLAEAE QTLGLPITDE QIQEMKSNLE NIDFKMAAEE EKRLRHDVMA HVHTFGHCCP KAAGIIHLGA TSCYVGDNTD LIILRNALDL LLPKLARVIS RLADFAKERA SLPTLGFTHF QPAQLTTVGK RCCLWIQDLC MDLQNLKRVR DDLRFRGVKG TTGTQASFLQ LFEGDDHKVE QLDKMVTEKA GFKRAFIITG QTYTRKVDIE VLSVLASLGA SVHKICTDIR LLANLKEMEE PFEKQQIGSS AMPYKRNPMR SERCCSLARH

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human ADSL (NP_000017.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:20 - 1:100,IP,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Adenylosuccinate Lyase

Antigène: Adenylosuccinate Lyase (ADSL)

Autre désignation: ADSL (ADSL Produits)

Synonymes: anticorps fi60b04, anticorps zgc:56061, anticorps wu:fi60b04, anticorps MGC53383, anticorps MGC69239, anticorps adsL, anticorps F15C21.8, anticorps F15C21_8, anticorps AMPS, anticorps ASASE, anticorps ASL, anticorps Adl, anticorps Asl, anticorps purB, anticorps adenylosuccinate lyase, anticorps adenylosuccinate lyase L homeolog, anticorps adenylosuccinase; ASL, anticorps Adenylosuccinate lyase, anticorps L-Aspartase-like family protein, anticorps ADSL, anticorps adsl, anticorps adsl.L, anticorps ASL, anticorps purB, anticorps purB,adsL, anticorps Mrub_2293, anticorps MMAH_RS02975, anticorps Arnit_0089, anticorps Mesil_1058, anticorps Slip_0597, anticorps Trad_2452, anticorps Deba_0652, anticorps Toce_1174, anticorps Acear_2324, anticorps Igag_0272, anticorps Saut_2156, anticorps Fbal_1996, anticorps Ndas_2434, anticorps Ilyop_0196, anticorps Lbys_2961, anticorps MFER_RS02920, anticorps Palpr_2192, anticorps Calni_0061, anticorps Ftrac_3746, anticorps AT1G36280, anticorps Olsu_1764, anticorps Adsl

Sujet: The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene.,ADSL,AMPS,ASASE,ASL,Signal Transduction,Endocrine & Metabolism,ADSL

Poids moléculaire: 48 kDa/54 kDa

ID gène: 158

UniProt: P30566

Pathways: Ribonucleoside Biosynthetic Process