Angiotensin II Type-1 Receptor anticorps (AA 250-350)

N° du produit ABIN6136653

Détail du produit anti-Angiotensin II Type-1 Receptor anticorps

Antigène: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Épitope: AA 250-350

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiotensin II Type-1 Receptor est non-conjugé

Application: Western Blotting (WB)

Séquence: FFSWIPHQIF TFLDVLIQLG IIRDCRIADI VDTAMPITIC IAYFNNCLNP LFYGFLGKKF KRYFLQLLKY IPPKAKSHSN LSTKMSTLSY RPSDNVSSST K

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human AT1R/AGTR1 (NP_000676.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Angiotensin II Type-1 Receptor

Antigène: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Autre désignation: AGTR1 (AGTR1 Produits)

Synonymes: anticorps AG2S, anticorps AGTR1A, anticorps AGTR1B, anticorps AT1, anticorps AT1AR, anticorps AT1B, anticorps AT1BR, anticorps AT1R, anticorps AT2R1, anticorps AT2R1A, anticorps AT2R1B, anticorps HAT1R, anticorps 1810074K20Rik, anticorps AI551199, anticorps AT1a, anticorps Agtr-1a, anticorps Agtr1, anticorps Angtr-1a, anticorps AT1A, anticorps XAT-1, anticorps agtr1-A, anticorps agtr1.2, anticorps AT1-R, anticorps at1, anticorps AGTR1, anticorps Agtr-1b, anticorps Angtr-1b, anticorps agtr1, anticorps agtr1-a, anticorps agtr1-b, anticorps xAT, anticorps angiotensin II receptor type 1, anticorps angiotensin II receptor, type 1a, anticorps angiotensin II receptor type 1 S homeolog, anticorps uncharacterized AGTR1, anticorps angiotensin II receptor, type 1b, anticorps angiotensin II receptor type 1 L homeolog, anticorps AGTR1, anticorps Agtr1a, anticorps agtr1.S, anticorps Agtr1, anticorps Agtr1b, anticorps agtr1.L

Sujet: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.,AGTR1,AG2S,AGTR1B,AT1,AT1AR,AT1B,AT1BR,AT1R,AT2R1,HAT1R,Cancer,Invasion and Metastasis,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Cardiovascular,Angiogenesis,Angiogenic growth factors,Blood,Blood Pressure regulation,AGTR1

Poids moléculaire: 41 kDa

ID gène: 185

UniProt: P30556

Pathways: Signalistation JAK/STAT, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour