Cyclin A anticorps

N° du produit ABIN6138073

Détail du produit anti-Cyclin A anticorps

Antigène: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide of human Cyclin A2

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Cyclin A (ABIN6138073)

Sun, Xie, Xu, Cai, Zhang, Cui, Zheng, Zhou: "Advanced oxidation protein products induce S-phase arrest of hepatocytes via the ROS-dependent, β-catenin-CDK2-mediated pathway." dans: Redox biology, Vol. 14, pp. 338-353, (2018) (PubMed).

Yu, Pang, Wu, Lin, Tseng, Tsai: "Platelet-rich plasma increases proliferation of tendon cells by modulating Stat3 and p27 to up-regulate expression of cyclins and cyclin-dependent kinases." dans: Cell proliferation, Vol. 48, Issue 4, pp. 413-20, (2015) (PubMed).

Détails sur Cyclin A

Antigène: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Autre désignation: CCNA2 (CCNA2 Produits)

Synonymes: anticorps CCN1, anticorps CCNA, anticorps AA408589, anticorps Ccn-1, anticorps Ccn1, anticorps Ccna, anticorps CycA2, anticorps Cyca, anticorps cb671, anticorps chunp6924, anticorps wu:fi36f03, anticorps CYCA, anticorps Cyclin-A2, anticorps ccna2, anticorps ccn1, anticorps ccna, anticorps ccna1, anticorps Cyclin-A, anticorps cyclinA, anticorps cyclin A2, anticorps cyclin A2 S homeolog, anticorps cyclin A2 L homeolog, anticorps CCNA2, anticorps Ccna2, anticorps ccna2, anticorps ccna2.S, anticorps ccna2.L

Sujet: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.,CCN1,CCNA,Cyclin A2,CCNA2,cyclin-A2,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cyclins,Endocrine & Metabolism,AMPK Signaling Pathway,Cardiovascular,Lipids,Lipoproteins/Apolipoproteins,CCNA2

Poids moléculaire: 48 kDa

ID gène: 890

UniProt: P20248

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA