Casein Kinase 1 gamma 2 anticorps (AA 316-415)

N° du produit ABIN6139122

Détail du produit anti-Casein Kinase 1 gamma 2 anticorps

Antigène: Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))

Épitope: AA 316-415

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Casein Kinase 1 gamma 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: FDRSGFVFDY EYDWAGKPLP TPIGTVHTDL PSQPQLRDKT QPHSKNQALN STNGELNADD PTAGHSNAPI TAPAEVEVAD ETKCCCFFKR RKRKSLQRHK

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 316-415 of human CSNK1G2 (NP_001310.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Casein Kinase 1 gamma 2

Antigène: Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))

Autre désignation: CSNK1G2 (CSNK1G2 Produits)

Synonymes: anticorps CK1g2, anticorps 2810429I12Rik, anticorps AI463719, anticorps CKI, anticorps ck1-gamma, anticorps CSNK1G2, anticorps ck1g2, anticorps csnk1g2, anticorps fj97g11, anticorps wu:fj97g11, anticorps wz8345, anticorps zgc:110719, anticorps zgc:153415, anticorps casein kinase 1 gamma 2, anticorps casein kinase 1, gamma 2, anticorps casein kinase 1 gamma 2 L homeolog, anticorps casein kinase 1, gamma 2a, anticorps casein kinase 1, gamma 2b, anticorps CSNK1G2, anticorps Csnk1g2, anticorps csnk1g2.L, anticorps csnk1g2, anticorps csnk1g2a, anticorps csnk1g2b

Sujet: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.,CSNK1G2,CK1g2,Cancer,Signal Transduction,Kinase,Endocrine & Metabolism,Lipid Metabolism,Stem Cells,CSNK1G2

Poids moléculaire: 47 kDa

ID gène: 1455

UniProt: P78368

Pathways: Signalisation Hedgehog