ERCC3 anticorps (AA 512-782)
Aperçu rapide pour ERCC3 anticorps (AA 512-782) (ABIN6140267)
Antigène
Voir toutes ERCC3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 512-782
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Séquence
- CPMSPEFYRE YVAIKTKKRI LLYTMNPNKF RACQFLIKFH ERRNDKIIVF ADNVFALKEY AIRLNKPYIY GPTSQGERMQ ILQNFKHNPK INTIFISKVG DTSFDLPEAN VLIQISSHGG SRRQEAQRLG RVLRAKKGMV AEEYNAFFYS LVSQDTQEMA YSTKRQRFLV DQGYSFKVIT KLAGMEEEDL AFSTKEEQQQ LLQKVLAATD LDAEEEVVAG EFGSRSSQAS RRFGTMSSMS GADDTVYMEY HSSRSKAPSK HVHPLFKRFR K
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 512-782 of human ERCC3 (NP_000113.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))
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Autre désignation
- ERCC3
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Sujet
- This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.,ERCC3,BTF2,GTF2H,RAD25,TFIIH,TTD2,XPB,Epigenetics & Nuclear Signaling,Transcription Factors,DNA Damage & Repair,Cancer,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Nucleotide metabolism,Purine and pyrimidine synthesis,ERCC3
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Poids moléculaire
- 89 kDa
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ID gène
- 2071
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UniProt
- P19447
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Pathways
- Réparation de l'ADN
Antigène
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